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Prevalence of polypoidal choroidal vasculopathy using non-ICGA based criteria

Published:September 24, 2021DOI:https://doi.org/10.1016/j.oret.2021.09.009

      Abstract

      Polypoidal choroidal vasculopathy (PCV) is a form of neovascular AMD characterized by polypoidal lesions and branching vascular networks. Diagnosis has traditionally required the use of invasive indocyanine green angiography, though recently a validated non-invasive diagnostic system has been developed that identified PCV-specific features using optical coherence tomography (OCT) and color fundus photography. In this work we applied this new system to a large population-based cohort of ethnic Chinese and successfully identified PCV and related anatomical features. We estimated a population prevalence of 0.31% (95% CI, 0.06–0.91%) and additionally demonstrate that PCV-related retinal findings were relatively rare in the population.

      Key Words

      Abbreviations:

      AMD (age-related macular degeneration), AMD-CNV (AMD choroidal neovascularization), PCV (polypoidal choroidal vasculopathy)
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