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Prevalence of Polypoidal Choroidal Vasculopathy Using Non-indocyanine green angiography–based Criteria

Published:September 24, 2021DOI:https://doi.org/10.1016/j.oret.2021.09.009
      Polypoidal choroidal vasculopathy (PCV) is a form of neovascular age-related macular degeneration characterized by polypoidal lesions and branching vascular networks. Diagnosis has traditionally required the use of invasive indocyanine green angiography; however, recently, a validated noninvasive diagnostic system has been developed that identifies PCV-specific features using OCT and color fundus photography. In this work, we applied this new system to a large population-based ethnic Chinese cohort and successfully identified PCV and related anatomic features. We estimated a population prevalence of 0.31% (95% CI, 0.06%–0.91%) and demonstrated that PCV-related retinal findings were relatively rare in the population.

      Keywords

      Abbreviations and Acronyms:

      AMD (age-related macular degeneration), APOIS (Asia Pacific Ocular Imaging Society), CFP (color fundus photography), ICGA (indocyanine green angiography), PED (pigment epithelial detachment), PCV (polypoidal choroidal vasculopathy), RPE (retinal pigment epithelium)
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      References

        • Chen S.J.
        • Cheng C.Y.
        • Peng K.L.
        • et al.
        Prevalence and associated risk factors of age-related macular degeneration in an elderly Chinese population in Taiwan: the Shihpai Eye Study.
        Invest Ophthalmol Vis Sci. 2008; 49: 3126-3133
        • Smith W.
        • Assink J.
        • Klein R.
        • et al.
        Risk factors for age-related macular degeneration: pooled findings from three continents.
        Ophthalmology. 2001; 108: 697-704
        • Kawasaki R.
        • Yasuda M.
        • Song S.J.
        • et al.
        The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis.
        Ophthalmology. 2010; 117: 921-927
        • Cheung C.M.G.
        • Lai T.Y.Y.
        • Teo K.
        • et al.
        Polypoidal choroidal vasculopathy: consensus nomenclature and non-indocyanine green angiograph diagnostic criteria from the Asia-Pacific Ocular Imaging Society PCV Workgroup.
        Ophthalmology. 2021; 128: 443-452
        • Majithia S.
        • Tham Y.C.
        • Chee M.L.
        • et al.
        Singapore Chinese Eye Study: key findings from baseline examination and the rationale, methodology of the 6-year follow-up series.
        Br J Ophthalmol. 2020; 104: 610-615
        • Li Y.
        • You Q.S.
        • Wei W.B.
        • et al.
        Polypoidal choroidal vasculopathy in adult Chinese: the Beijing Eye Study.
        Ophthalmology. 2014; 121: 2290-2291